NIFK Rabbit Polyclonal Antibody

CAT#: AP20259PU-N

NIFK rabbit polyclonal antibody, Aff - Purified

Product Images

Immunohistochemistry analyzes of NIFK antibody (AP20259PU-N) in paraffin-embedded human lung carcinoma tissue.

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunohistochemistry on paraffin sections: 1/50-1/200.
  Immunoflourescence: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of NIFK protein.
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Gene Name: Homo sapiens nucleolar protein interacting with the FHA domain of MKI67 (NIFK)
• Database Link:
  Entrez Gene 67949 MouseEntrez Gene 84365 Human
• Background: The structural proteins for the complex metalloenzyme nitrogenase include NIFK, NIFD and NIFH. These proteins are all necessary for archaeal and bacterial nitrogen fixation. The NIFK gene encodes the b subunit of the nitrogenase molybdenum-iron (MoFe) tetramer. NIFK localizes to the nucleolus where it interactes with the fork-head associated domain of the proliferation marker protein Ki-67 in a mitosis-specific and phosphorylation-dependent manner. NIFK is widely expressed in adult tissues, suggesting other functions in addition to its interaction with Ki-67, which is only expressed in proliferating cells.
• Synonyms: MKI67IP, NOPP34

Reference Data

• Protein Families: Transcription Factors