FOXO4 Rabbit Polyclonal Antibody

CAT#: AP20362PU-N

FOXO4 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of FoxO4 antibody (AP20362PU-N) in extracts from K562 cells

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunofluorecence: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of FoxO4 protein.
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 55, 70 kDa
• Gene Name: Homo sapiens forkhead box O4 (FOXO4), transcript variant 1
• Database Link:
  Entrez Gene 54601 MouseEntrez Gene 4303 Human
  UniProt ID P98177
• Background: FOX4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.
• Synonyms: Forkhead box protein O4

Reference Data

• Protein Families: Transcription Factors