SOX6 Rabbit Polyclonal Antibody

CAT#: AP20382PU-N

SOX6 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Sox-6 antibody (Cat.-No.: AP20382PU-N) in extracts from Jurkat cells.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunohistochmistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Sox-6 protein.
  (region surrounding Asp23)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Predicted Protein Size: ~ 91 kDa
• Gene Name: Homo sapiens SRY-box 6 (SOX6), transcript variant 1
• Database Link:
  Entrez Gene 20679 MouseEntrez Gene 293165 RatEntrez Gene 55553 Human
• Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
• Synonyms: Transcription factor SOX-6, SRY-box 6, HSSOX6, SOXD

Reference Data

• Protein Families: Transcription Factors