TRIM38 Rabbit Polyclonal Antibody

CAT#: AP20399PU-N

TRIM38 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analyzes of RNF15 antibody (Cat.-No.: AP20399PU-N) in extracts from MCF7 cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of RNF15 protein.
  (region surrounding Glu193)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction > 95% (by SDS-PAGE)
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 58 kDa
• Gene Name: Homo sapiens tripartite motif containing 38 (TRIM38)
• Database Link:
  Entrez Gene 214158 MouseEntrez Gene 10475 Human
  UniProt ID O00635
• Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF152 (RINGfinger protein 152) is a 203 amino acid protein that contains one RING-type zinc finger and may be involved in protein degradation events throughout the cell. The gene encoding RNF152 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18- localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasi,a erythropoietic protoporphyria and follicular lymphomas.
• Synonyms: RORET, RING finger protein 15

Reference Data

• Protein Families: Druggable Genome