TPTEP2-CSNK1E Rabbit Polyclonal Antibody

CAT#: AP20419PU-N

TPTEP2-CSNK1E rabbit polyclonal antibody, Aff - Purified


USD 407.00

2 Weeks*

Size
    • 100 ug

Product Images

Other products for "CK1 epsilon"

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution Western blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections: 1/50-1/200.
Immunofluorescence: 1/50-1/200.
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 250-350 of Human Casein Kinase Iε.
Specificity This antibody detects endogenous levels of Casein Kinase Iε protein.
(region surrounding Pro301)
Formulation Phosphate buffered saline (PBS), pH 7.2
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration 1.0 mg/ml
Purification Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Predicted Protein Size ~ 47 kDa
Gene Name Homo sapiens casein kinase 1 epsilon (CSNK1E), transcript variant 2
Background Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, ε and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The α catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
Synonyms CKI-epsilon, CKIe, CSNK1E
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Circadian rhythm - mammal, Hedgehog signaling pathway, Wnt signaling pathway

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.