KLF1 (+GKLF) Rabbit Polyclonal Antibody

CAT#: AP20438PU-N

KLF1 (+GKLF) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of EKLF/GKLF antibody (Cat.-No.: AP20438PU-N) in extracts from Jurkat cell treated with serum 20% 15'

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of EKLF/GKLF protein.
  (region surrounding Trp318)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 38 kDa
• Gene Name: Homo sapiens Kruppel-like factor 1 (erythroid) (KLF1)
• Database Link:
  Entrez Gene 16596 MouseEntrez Gene 304666 RatEntrez Gene 10661 Human
  UniProt ID Q13351
• Background: The Kruppel-type zinc finger transcription factors comprise a conserved family of DNA binding proteins that are important in developmental regulation. The Kruppel zinc finger transcription factor was initially identified in Drosophila as a segmentation gene. Kruppel-like factors that have been characterized in mammals include EKLF, LKLF and GKLF (6-8). EKLF is expressed principally in erythroid tissues, and LKLF expression is limited to the lung. GKLF is found predominantly in gut and has been shown to be expressed during growth arrest.
• Synonyms: KLF1, EKLF, Krueppel-like factor 1, Erythroid transcription factor, KLF-1

Reference Data

• Protein Families: Transcription Factors