CSNK1G1 Rabbit Polyclonal Antibody

CAT#: AP20461PU-N

CSNK1G1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Casein Kinase Igamma1 antibody (Cat.-No.: AP20461PU-N) in extracts from COS-7 cells.

• 

  Immunohistochemistry (IHC) analyzes of Casein Kinase Igamma1 antibody (Cat.-No.: AP20461PU-N)in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
  Immunofluorescence: 1/50 - 1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Casein Kinase Igamma1 protein.
  (region surrounding His3)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 49 kDa
• Gene Name: Homo sapiens casein kinase 1 gamma 1 (CSNK1G1)
• Database Link:
  Entrez Gene 64086 RatEntrez Gene 214897 MouseEntrez Gene 53944 Human
  UniProt ID Q9HCP0
• Background: Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIalpha, gamma, epsilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2-beta2 or an alpha-alpha'beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
• Synonyms: Casein kinase I isoform gamma-1, CKI-gamma 1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Hedgehog signaling pathway