RAD51C Rabbit Polyclonal Antibody

CAT#: AP20492PU-N

RAD51C rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Rad51C antibody (Cat.-No.: AP20492PU-N) in extracts from COS-7 cells.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Rad51C protein.
  (region surrounding Glu185)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~50 kDa
• Gene Name: Homo sapiens RAD51 paralog C (RAD51C), transcript variant 1
• Database Link:
  Entrez Gene 5889 Human
• Background: The process of homologous recombination is a major DNA repair pathway that operates on DNA double-strand breaks to promote error-free repair. Human Rad51 protein assembles on a DNA molecule through cooperative binding and forms a long filament for homologous recombination. In addition to Rad51 protein, five paralogs have been identified in vertebrates, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3. Rad51C binds single- and double-stranded DNA and preferentially binds 3'-end-tailed double-stranded DNA. Rad51C is expressed in a variety of tissues, with highest expression in testis, heart muscle, spleen and prostate.
• Synonyms: RAD51L2, R51H3, RAD51 homolog C, RAD51-like protein 2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination