RBM5 Rabbit Polyclonal Antibody

CAT#: AP20525PU-N

RBM5 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of LUCA15 antibody (Cat.-No.: AP20525PU-N) in extracts from HHUVEC cells.

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  Immunohistochemistry (IHC) analyzes of LUCA15 antibody (Cat.-No.: AP20525PU-N) in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of LUCA15 protein.
  (region surrounding asn261)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Predicted Protein Size: ~ 92 kDa
• Gene Name: Homo sapiens RNA binding motif protein 5 (RBM5), transcript variant 1
• Database Link:
  Entrez Gene 83486 MouseEntrez Gene 10181 Human
• Background: DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similiar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.
• Synonyms: RNA-binding protein 5, NY-REN-9

Reference Data

• Protein Families: Druggable Genome