PITX1 Rabbit Polyclonal Antibody

CAT#: AP20531PU-N

PITX1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Pitx1 antibody (Cat.-No.: AP20531PU-N) in extracts from Jurkat cells.

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  Immunohistochemistry (IHC) analyzes of Pitx1 antibody (Cat.-No.: AP20531PU-N) in paraffin-embedded human lung carcinoma tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Pitx1 protein.
  (region surrounding Glu130)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 34 kDa
• Gene Name: Homo sapiens paired like homeodomain 1 (PITX1)
• Database Link:
  Entrez Gene 18740 MouseEntrez Gene 113983 RatEntrez Gene 5307 Human
  UniProt ID P78337
• Background: Pitx1 and Pitx2 are highly homologous, bicoid-related transcription factors. Pitx1 is a bicoid-related homeodomain factor that exhibits preferential expression in the hindlimb, as well as expression in the developing anterior pituitary gland and first branchial arch. Deletion of the Pitx1 locus results in decreased distal expression of the hindlimb-specific marker, the T-box factor (Tbx4). Pitx1 may modulate morphogenesis, growth and patterning of a specific hindlimb region, and serves as a component of the variables that influence morphological and growth distinctions in forelimb and hindlimb identity.
• Synonyms: Pituitary homeobox 1, BFT, PTX1

Reference Data

• Protein Families: Transcription Factors