COX17 Rabbit Polyclonal Antibody

CAT#: AP20541PU-N

COX17 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of COX17 antibody in extracts from HeLa cells.

• 

  Immunohistochemistry (IHC) analyzes of COX17 antibody in paraffin-embedded human liver carcinoma tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to the N-terminal of Human Cox-17.
• Specificity: This antibody detects endogenous levels of COX17 protein.
  (region surrounding Asn8)
• Formulation: PBS, pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 7 kDa
• Gene Name: Homo sapiens COX17, cytochrome c oxidase copper chaperone (COX17)
• Database Link:
  Entrez Gene 12856 MouseEntrez Gene 89786 RatEntrez Gene 10063 Human
  UniProt ID Q14061
• Background: Cytochrome c oxidase 17 (COX17) is a nuclear gene encoding an assembly protein necessary for proper COX apoenzyme-dependent mitochondrial respiration. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial genes that encode catalytic subunits and several nuclear genes that encode structural subunits. COX17 influences the recruitment of copper to the mitochondria for incorporation into the COX apoenzyme.
• Synonyms: COX-17

Reference Data

• Protein Pathways: Metabolic pathways, Oxidative phosphorylation