Annexin A1 (ANXA1) Rabbit Polyclonal Antibody

CAT#: AP20568PU-N

Annexin A1 (ANXA1) rabbit polyclonal antibody, Aff - Purified

Product Images

Immunohistochemistry (IHC) analyzes of Annecin I antibody (Cat.-No.: AP20568PU-N) in paraffin-embedded human brain tissue.

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  Western blot (WB) analysis of Annexin I antibody (Cat.-No.: AP20568PU-N) in extracts from HeLa cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Annexin I protein.
  (region surrounding asn146)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 39 kDa
• Gene Name: Homo sapiens annexin A1 (ANXA1)
• Database Link:
  Entrez Gene 16952 MouseEntrez Gene 25380 RatEntrez Gene 301 Human
• Background: During apoptosis, phosphatidylserine (PS) is translocated from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca2+-dependent affinity for PS and therefore is used as a probe for detecting apoptosis. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V is associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc).
• Synonyms: ANX1, LPC1, Annexin-1, Annexin I, Lipocortin I, Calpactin II, Chromobindin-9, p35

Reference Data

• Protein Families: Druggable Genome