Carbonic Anhydrase II (CA2) Rabbit Polyclonal Antibody

CAT#: AP20569PU-N

Carbonic Anhydrase II (CA2) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Carbonic anhydrase 2 antibody (Cat.-No AP20569PU-N) in extracts from rat heart cells.

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  Immunohistochemistry analyzes of Carbonic anhydrase 2 antibody (Cat.-No AP20569PU-N) in paraffin-embedded human lung carcinoma tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 201-250 of Human CA II.
• Specificity: This antibody detects endogenous levels of CA II protein.
  (region surrounding asn229)
• Formulation: Phosphate Buffered Saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction is (> 95% pure by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 28 kDa
• Gene Name: Homo sapiens carbonic anhydrase 2 (CA2), transcript variant 1
• Database Link:
  Entrez Gene 760 Human
• Background: Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes including respiration, calcification, acid-base balance and bone resorption, as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. The human CA2 gene, which maps to chromosome 8q21, encodes CA II, a cytoplasmic protein that has the highest turnover rate and widest tissue distribution of any known human CA isozyme.
• Synonyms: Carbonic anhydrase II, Carbonate dehydratase II, Carbonic anhydrase C, CA2, CA-II, CAC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nitrogen metabolism