Cathepsin G (CTSG) Rabbit Polyclonal Antibody

CAT#: AP20583PU-N

Cathepsin G (CTSG) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Cathepsin G antibody in extracts from Hela cells.

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  Immunohistochemistry analysis of Cathepsin G antibody in paraffin-embedded human spleen tissue at 1/100.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 71-120 of Human Cathepsin G.
• Specificity: This antibody detects endogenous levels of Cathepsin G protein.
  (region surrounding Arg116)
• Formulation: PBS, pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 30 kDa
• Gene Name: cathepsin G
• Database Link:
  Entrez Gene 1511 Human
  UniProt ID P08311
• Background: Cathepsin G is a serine protease, it consisting of a single polypeptide with a molecular weight of 30 kDa as determined by SDS-PAGE. Its substrates are collagen and proteoglycans. Poor regulation of Cathepsin G levels has been associated with various connective tissue disorders, for example pulmonary emphysema and cystic fibrosis.
• Synonyms: CTSG, VSP

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome, Neuroactive ligand-receptor interaction, Renin-angiotensin system, Systemic lupus erythematosus