Cholecystokinin (CCK) Rabbit Polyclonal Antibody

CAT#: AP20643PU-N

Cholecystokinin (CCK) rabbit polyclonal antibody, Aff - Purified

Product Images

Immunohistochemistry analyzes of CCK antibody in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 21-70 of Human CCK.
• Specificity: This antibody detects endogenous levels of CCK protein.
  (region surrounding Val46)
• Formulation: Phosphate buffered saline (PBS), pH~7.2 with 0.02% Sodium Azide and 50% Glycerol.
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~13 kDa
• Gene Name: cholecystokinin
• Database Link:
  Entrez Gene 12424 MouseEntrez Gene 25298 RatEntrez Gene 885 Human
  UniProt ID P06307
• Background: CCK (cholecystokinin) is a 115 amino acid secreted protein belonging to the gastrin/cholecystokinin family. CCK has been shown to stimulate the growth of pancreatic cancer. As a peptide hormone, CCK induces gallbladder contraction and the release of pancreatic enzymes in the gut. Binding of CCK to CCK-A receptors stimulates amylase release from the pancreas, while binding to CCK-B receptors stimulates gastric acid secretion. The function of CCK in the brain is not clear. The CCK precursor is cleaved by proteases to produce a number of active cholecystokinins including CCK58, CCK58 desnonopeptide, CCK39, CCK33, CCK25, CCK18, CCK12, CCK8, CCK7 and CCK5.
• Synonyms: cholecystokinin; MGC117187; OTTHUMP00000209369

Reference Data

• Protein Families: Druggable Genome, Secreted Protein