Cholecystokinin (CCK) Rabbit Polyclonal Antibody
Other products for "CCK"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | Immunohistochemistry on Paraffin Sections: 1/50-1/200 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 21-70 of Human CCK. |
Specificity | This antibody detects endogenous levels of CCK protein. (region surrounding Val46) |
Formulation | Phosphate buffered saline (PBS), pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 0.05% Sodium Azide |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography using epitope-specific immunogen |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | ~13 kDa |
Gene Name | Homo sapiens cholecystokinin (CCK), transcript variant 1 |
Database Link | |
Background | CCK (cholecystokinin) is a 115 amino acid secreted protein belonging to the gastrin/cholecystokinin family. CCK has been shown to stimulate the growth of pancreatic cancer. As a peptide hormone, CCK induces gallbladder contraction and the release of pancreatic enzymes in the gut. Binding of CCK to CCK-A receptors stimulates amylase release from the pancreas, while binding to CCK-B receptors stimulates gastric acid secretion. The function of CCK in the brain is not clear. The CCK precursor is cleaved by proteases to produce a number of active cholecystokinins including CCK58, CCK58 desnonopeptide, CCK39, CCK33, CCK25, CCK18, CCK12, CCK8, CCK7 and CCK5. |
Synonyms | cholecystokinin; MGC117187; OTTHUMP00000209369 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
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