KCNMA1 Rabbit Polyclonal Antibody

CAT#: AP20653PU-N

KCNMA1 rabbit polyclonal antibody, Aff - Purified


USD 370.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Western Blot: 1/500-1/1000.
Immunohistochemistry on paraffin sections
: 1/50-1/200.
Reactivities Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 750-800 of Human MaxiKα
Specificity This antibody detects endogenous levels of MaxiKα protein.
(region surrounding Gln770)
Formulation Phosphate buffered saline (PBS), pH 7.2
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration 1.0 mg/ml
Purification Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Predicted Protein Size ~ 137 kDa
Gene Name Homo sapiens potassium calcium-activated channel subfamily M alpha 1 (KCNMA1), transcript variant 1
Background MaxiK channels are large conductance, voltage and calciumsensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the poreforming alpha subunit and the modulatory beta subunit. KCNMB2 is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents.
Synonyms Maxi K, BK, K VCA, BKCA channel, Slowpoke homolog, Slo-alpha, Slo1, hSlo
Reference Data
Protein Families Druggable Genome, Ion Channels: Potassium, Transmembrane
Protein Pathways Vascular smooth muscle contraction

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.