Semaphorin 3A (SEMA3A) Rabbit Polyclonal Antibody

CAT#: AP20784PU-N

Semaphorin 3A (SEMA3A) rabbit polyclonal antibody, Aff - Purified

Product Images

Immunohistochemistry (IHC) analyzes of SEMA3A antibody (Cat.-No.: AP20784PU-N) in paraffin-embedded human lung carcinoma tissue.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 702-756 of Human SEMA3A.
• Specificity: This antibody detects endogenous levels of SEMA3A protein.
  (region surrounding Pro737)
• Formulation: PBS, pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~89 kDa
• Gene Name: Homo sapiens semaphorin 3A (SEMA3A)
• Database Link:
  Entrez Gene 10371 Human
  UniProt ID Q14563
• Background: Semaphorin 3A (Sema3A) may play a particularly interesting role in limiting axon regeneration since it is expressed in meningeal fibroblasts that invade the injured spinal cord and surround the glial scar. In addition, the Sema3A co receptors, Neuropilin 1 and Plexin A1, are expressed on axons that regenerate up to the injured region, but do not cross this Sema3A containing region. Thus, Sema3A and its co receptors may have important roles in regulating axon guidance during neuronal development and after neuronal injury.
• Synonyms: Semaphorin-3A, Semaphorin III, Sema III, SEMAD

Reference Data

• Protein Families: Secreted Protein
• Protein Pathways: Axon guidance