GNPAT Rabbit Polyclonal Antibody

CAT#: AP21060PU-N

GNPAT rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of GNPAT antibody (Cat.-No.: AP21060PU-N) in extracts from HT-29 cells.

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  Immunohistochemistry (IHC) analyzes of GNPAT antibody (Cat.-No.: AP21060PU-N) in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of GNPAT protein.
  (region surrounding Phe365)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 77 kDa
• Gene Name: Homo sapiens glyceronephosphate O-acyltransferase (GNPAT)
• Database Link:
  Entrez Gene 8443 Human
  UniProt ID O15228
• Background: GNPAT is a key enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata type 2, which is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.
• Synonyms: DHAPAT, Dihydroxyacetone phosphate acyltransferase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Glycerophospholipid metabolism