MRPS21 Rabbit Polyclonal Antibody

CAT#: AP21072PU-N

MRPS21 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of MRP-S21 Antibody (Cat.-No AP21072PU-N) in extracts from COS cells.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of MRP-S21 protein.
  (region surrounding Gln85)
• Formulation: Phosphate buffered saline (PBS), PH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Predicted Protein Size: ~11 kDa
• Gene Name: Homo sapiens mitochondrial ribosomal protein S21 (MRPS21), transcript variant 2
• Database Link:
  Entrez Gene 66292 MouseEntrez Gene 689432 RatEntrez Gene 54460 Human
• Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein.
• Synonyms: S21mt, MRP-S21, RPMS21, MDS016