ME3 Rabbit Polyclonal Antibody

CAT#: AP21077PU-N

ME3 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of ME3 antibody (Cat.-No.: AP21077PU-N) in extracts from RAW264 cells.

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  Immunohistochemistry (IHC) analyzes of ME3 antibody (Cat.-No.: AP21077PU-N) in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of ME3 protein.
  (region surrounding Arg576)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 67 kDa
• Gene Name: Homo sapiens malic enzyme 3, NADP(+)-dependent, mitochondrial (ME3), transcript variant 2
• Database Link:
  Entrez Gene 109264 MouseEntrez Gene 10873 Human
  UniProt ID Q16798
• Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis, metastasis, and atherosclerosis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
• Synonyms: NADP-ME

Reference Data

• Protein Pathways: Metabolic pathways, Pyruvate metabolism