CLIC3 Rabbit Polyclonal Antibody

CAT#: AP21147PU-N

CLIC3 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of CLIC3 antibody (Cat.-No.: AP21147PU-N) in extracts from MCF-7 cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of CLIC3 protein.
  (region surrounding Phe56)
• Formulation: Phosphate buffered saline (PBS), pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 27 kDa
• Gene Name: Homo sapiens chloride intracellular channel 3 (CLIC3)
• Database Link:
  Entrez Gene 9022 Human
  UniProt ID O95833
• Background: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
• Synonyms: CLIC3

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other