Complement C9 (C9) Rabbit Polyclonal Antibody

CAT#: AP21155PU-N

Complement C9 (C9) rabbit polyclonal antibody, Aff - Purified


USD 407.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution Western blot: 1/500 - 1/1000.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Specificity This antibody detects endogenous levels of C9 protein.
(region surrounding His216)
Formulation Phosphate buffered saline (PBS), pH 7.2.
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.05% sodium azide
Concentration 1.0 mg/ml
Purification Affinity chromatography (> 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Predicted Protein Size ~ 70 kDa
Gene Name Homo sapiens complement component 9 (C9)
Background C9 is synthesised in the liver and monocytes, and is a plasma protein consisting of a single polypeptide chain of molecular weight 71kDa. Normal plasma concentration is 60mg/L. C9 forms part of the membrane attack complex (MAC) the cytolytic terminal complex of the complement pathways. C9 binds to the membrane associated C5b-8, binding of C9 to C5b-8 leads to the circular polymerisation of 12-18 C9 molecules. This is the basis of the hydrophilic, proteinwalled, trans-membrane channel formed by the MAC, which leads to cell lysis and destruction.
Synonyms Complement component C9, Complement 9
Reference Data
Protein Families Druggable Genome
Protein Pathways Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.