Glutathione S Transferase theta 1 (GSTT1) (+GSTT4) Rabbit Polyclonal Antibody

CAT#: AP21182PU-N

Glutathione S Transferase theta 1 (GSTT1) (+GSTT4) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of GSTT1/4 antibody (Cat.-No.: AP21182PU-N) in extracts from Jurkat cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of GSTT1/4 protein.
  (region surrounding Arg31)
• Formulation: Phosphate buffered saline (PBS), pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 30 kDa
• Gene Name: Homo sapiens glutathione S-transferase theta 1 (GSTT1), transcript variant 1
• Database Link:
  Entrez Gene 2952 Human
  UniProt ID P30711
• Background: The GST superfamily is made up of several subfamilies. Glutathione Stransferase P (GSTP1) belongs to the π subfamily and is involved in the conjugation of reduced glutathione to a variety of endogenous and exogenous hydrophobic electrophiles. Glutathione S-transferase μ 1 (GSTM1) is a cytoplasmic liver protein belonging to the μ family and has the same basic functions as GSTP1-1. Glutathione S-transferase θ 1 (GSTT1), a cytoplasmic homodimer belonging to the θ family, is expressed in erythrocytes. It is active in the reduced glutathione conjugation and also displays glutathione peroxidase activity with cumene hydroperoxide.
• Synonyms: Glutathione S-transferase theta-1, GST class-theta-1, Glutathione transferase T1-1

Reference Data

• Protein Pathways: Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450