HFE Rabbit Polyclonal Antibody

CAT#: AP21189PU-N

HFE rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of HLA-H antibody (Cat.-No.: AP21189PU-N) in extracts from LOVO cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of HLA-H protein.
  (region surrounding Ile104)
• Formulation: Phosphate buffered saline (PBS), pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 40 kDa
• Gene Name: Homo sapiens hemochromatosis (HFE), transcript variant 1
• Database Link:
  Entrez Gene 3077 Human
  UniProt ID Q30201
• Background: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
• Synonyms: dJ221C16.10.1; hemochromatosis; HFE1; HH; HLA-H; HLAH; MGC103790; MVCD7

Reference Data

• Protein Families: Druggable Genome, Transmembrane