NMU Rabbit Polyclonal Antibody

CAT#: AP21204PU-N

NMU rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Neuromedin-U in extracts from HepG2 cells with AP21204PU-N.

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  Immunohistochemistry (IHC) analyzes of Neuromedin-U in paraffin-embedded human skeletal muscle tissue with AP21204PU-N.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1:50 - 1:200.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Neuromedin-U protein.
  (region surrounding Ile174)
• Formulation: Phosphate buffered saline (PBS), pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 22 kDa
• Gene Name: Homo sapiens neuromedin U (NMU), transcript variant 1
• Database Link:
  Entrez Gene 10874 Human
  UniProt ID P48645
• Background: Neuromedin U (NmU) is a vertebrate peptide which stimulates uterine smooth muscle contraction and causes selective vasoconstriction. Like most other active peptides, it is proteolytically processed from a larger precursor protein. The mature peptides are 8 (NmU-8) to 25 (NmU-25) residues long and C-terminally amidated. The sequence of the C-terminal extremity of NmU is extremely well conserved across species.
• Synonyms: Neuromedin U

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane