FOXC1 Goat Polyclonal Antibody

CAT#: AP22375PU-N

FOXC1 goat polyclonal antibody, Aff - Purified

Product Images

FOXC1 antibody staining of HEK293 lysate at 2ug/ml (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: Peptide ELISA: Detection Limit: 1/32000.
  Western blot: 2-4 µg/ml. Detects a band of ~55 kDa in lysates of cell line HEK293.
• Reactivities: Human, Mouse, Porcine
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Dynthetic peptide from an internal region of Human FOXC1 (NP_001444.2).
• Specificity: Recognizes FOXC1 (internal).
• Formulation: Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer.
  State: Aff - Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens forkhead box C1 (FOXC1)
• Database Link:
  Entrez Gene 17300 MouseEntrez Gene 2296 Human
• Background: FOXC1 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
• Synonyms: Forkhead box protein C1, FREAC-3
• Note: Calculated Molecular Weight: 56.8kDa (NP_001444.2).

Reference Data

• Protein Families: Druggable Genome, Transcription Factors