CD14 (71-84) Goat Polyclonal Antibody

CAT#: AP22502PU-N

CD14 (71-84) goat polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution ELISA: 1/128000.
Immunohistochemistry on Paraffin Sections: 4 µg/ml.
Western Blot: 1 - 3 µg/ml.
Reactivities Human
Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide from an internal region of human CD14 (NP_000582.1)
Specificity This antibody detects CD14 at aa 71-84.
Formulation Tris buffered saline, 0.5% BSA, 0.02% sodium azide
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Immunoaffinity chromatography
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens CD14 molecule (CD14), transcript variant 1
Background In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
Synonyms CD14
Reference Data
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Hematopoietic cell lineage, MAPK signaling pathway, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Toll-like receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.