Activin Receptor Type IA (ACVR1) (147-161) Goat Polyclonal Antibody

CAT#: AP22507PU-N

Activin Receptor Type IA (ACVR1) (147-161) goat polyclonal antibody, Aff - Purified

Product Images

Antibody (0.3 ug/ml) staining of Human Umbilical Cord lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Human Testis (formalin-fixed, paraffin-embedded) stained with ACVR1 antibody at 4 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/128000.
  Immunohistochemistry on Paraffin Sections: 4 µg/ml.
  Western Blot: 0.3 - 1 µg/ml.
• Reactivities: Bat, Bovine, Canine, Equine, Human, Monkey, Mouse, Porcine, Rabbit, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human ACVR1
• Specificity: This antibody detects Activin receptor type 1 (ACRV1) at aa 147-161.
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens activin A receptor type I (ACVR1), transcript variant 1
• Database Link:
  Entrez Gene 11477 MouseEntrez Gene 79558 RatEntrez Gene 90 Human
• Background: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors.
• Synonyms: Activin receptor type IA, ACVRLK2, ALK2, SKR1, ACRV1A

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, TGF-beta signaling pathway