Lactoferrin (LTF) (433-445) Goat Polyclonal Antibody

CAT#: AP22512PU-N

Lactoferrin (LTF) (433-445) goat polyclonal antibody, Aff - Purified

Product Images

LTF Antibody (0.05 ug/ml) staining of Peripheral Blood Mononucleocyte lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

• 

  Human Neutrophils (formalin-fixed, paraffin-embedded) stained with LTF antibody at 2 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/32000.
  Immunohistochemistry on Paraffin Sections: 2 µg/ml.
  Western Blot: 0.05 - 0.2 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Peptide from the internal region of the protein sequence according to NP_002334.2
• Specificity: This antibody detects Lactotransferrin at aa 433-445.
• Formulation: Tris saline, pH 7.3 containing 0.02% Sodium Azide and 0.5% BSA
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens lactotransferrin (LTF), transcript variant 1
• Database Link:
  Entrez Gene 4057 Human
• Background: Lactoferrin is an 80kDa non-haem, iron-binding globular glycoprotein and member of the transferrin family present in milk and mucosal secretions, and also released from neutrophil granules during inflammation. LTF acts as a major first line defense against microbial infections, partly due to its ability to efficiently bind to and hence remove Fe3+ from the environment, but studies have also shown that LTF possesses bactericidal properties and proteolytic activity, capable of cleaving arginine-rich sequences within microbial proteins. Three isoforms of LTF have been identified: LTF-alpha, LTF-beta and LTF-gamma and receptors for LTF are expressed in the gastrointestinal tract, by macrophages, lymphocytes, neutrophils and platelets and also by some bacteria.
• Synonyms: LTF, LF, Lactoferrin, EC=3.4.21, Talalactoferrin

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein