LIS1 (PAFAH1B1) (397-410) Goat Polyclonal Antibody

CAT#: AP22516PU-N

LIS1 (PAFAH1B1) (397-410) goat polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution ELISA: 1/32000.
Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Western Blot: 1 - 3 µg/ml.
Reactivities Bat, Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Xenopus, Zebrafish
Host Goat
Clonality Polyclonal
Immunogen Peptide from (C-term) of the protein sequence according to NP_000421
Specificity This antibody detects PAFAH1B1 / LIS1 at aa 397-410.
Formulation Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
State: Aff - Purified
State: Liquid Ig fracttion
Concentration lot specific
Purification Immunoaffinity chromatography
Storage Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens platelet activating factor acetylhydrolase 1b regulatory subunit 1 (PAFAH1B1)
Background PAFAH1B1 was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. PAFAH1B1 encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.
Synonyms PAF-AH alpha, PAFAH alpha, PAFAHA, Lissencephaly-1 protein, LIS-1, MDCR, MDS
Reference Data
Protein Pathways Ether lipid metabolism, Metabolic pathways

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