PCK1 (513-524) Goat Polyclonal Antibody

CAT#: AP22519PU-N

PCK1 (513-524) goat polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications ELISA, IHC
Recommended Dilution ELISA: 1/8000.
Immunohistochemistry on Paraffin Sections: 2 µg/ml.
Reactivities Bat, Canine, Equine, Human, Monkey, Rabbit
Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide from an internal region of human PCK1
Specificity This antibody detects PCK1 / PEPCK1 at aa 513-524.
Formulation Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Immunoaffinity chromatography
Storage Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens phosphoenolpyruvate carboxykinase 1 (PCK1)
Background PCK1 is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency.
Synonyms PEPCK-C, PEPCKC, Phosphoenolpyruvate carboxylase, PEP carboxykinase
Reference Data
Protein Families Druggable Genome
Protein Pathways Adipocytokine signaling pathway, Citrate cycle (TCA cycle), Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, PPAR signaling pathway, Pyruvate metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.