Perilipin-1 (PLIN1) (488-499) Goat Polyclonal Antibody

CAT#: AP22521PU-N

Perilipin-1 (PLIN1) (488-499) goat polyclonal antibody, Aff - Purified

Product Images

Antibody (0.01 ug/ml) staining of Human Adipose lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Human Colon (formalin-fixed, paraffin-embedded) stained with PLIN antibody at 2 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/128000.
  Immunohistochemistry on Paraffin Sections: 2 µg/ml.
  Western Blot: 0.01 µg/ml.
• Reactivities: Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from internal region of human PLIN
• Specificity: This antibody detects Perilipin-1 at aa 488-499.
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens perilipin 1 (PLIN1), transcript variant 1
• Database Link:
  Entrez Gene 5346 Human
• Background: Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.
• Synonyms: Perilipin, PLIN, PLIN1, PLIN-1, PERI

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: PPAR signaling pathway