PTBP1 (2-14) Goat Polyclonal Antibody

CAT#: AP22533PU-N

PTBP1 (2-14) goat polyclonal antibody, Aff - Purified

Product Images

Antibody staining (1 ug/ml) of Jurkat lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

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  Human Small Intestine (formalin-fixed, paraffin-embedded) stained with PTBP1 antibody at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Skin (formalin-fixed, paraffin-embedded) stained with PTBP1 antibody at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/8000.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/8000, 1 µg/ml.
• Reactivities: Bovine, Hamster, Human, Monkey, Mouse, Porcine, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from N-term of human PTBP1
• Specificity: This antibody detects PTBP1 (PTB) at aa 2-14.
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens polypyrimidine tract binding protein 1 (PTBP1), transcript variant 2
• Database Link:
  Entrez Gene 19205 MouseEntrez Gene 29497 RatEntrez Gene 5725 Human
• Background: PTBP1 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm.
• Synonyms: PPTB-1

Reference Data

• Protein Families: Druggable Genome