Prostaglandin dehydrogenase 1 (HPGD) (255-266) Goat Polyclonal Antibody

CAT#: AP22571PU-N

Prostaglandin dehydrogenase 1 (HPGD) (255-266) goat polyclonal antibody, Aff - Purified

Product Images

(0.1 ug/ml) staining of Human Duodenum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Human Colon (formalin-fixed, paraffin-embedded) stained with HPGD antibody followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Liver (formalin-fixed, paraffin-embedded) stained with HPGD antibody followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/128000.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 0.1 - 1 µg/ml.
• Reactivities: Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from the C-terminus of human HPGD / 15-PGDH (NP_000851.2)
• Specificity: This antibody detects C Terminus of Prostaglandin dehydrogenase 1.
• Formulation: Tris buffered saline ,pH 7.3, containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD), transcript variant 1
• Database Link:
  Entrez Gene 3248 Human
• Background: 15-PGDH / HPGD is a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: 15-hydroxyprostaglandin dehydrogenase, PGDH, PGDH1, Prostaglandin dehydrogenase 1

Reference Data

• Protein Families: Druggable Genome