NCF4 (228-238) Goat Polyclonal Antibody
Other products for "NCF4"
Specifications
Product Data | |
Applications | ELISA, IHC, WB |
Recommended Dilution | ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 2.5 µg/ml. Western Blot: 1/32000, 0.3 - 13 µg/ml. |
Reactivities | Equine, Human, Monkey |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Synthetic peptide from an internal region of human NCF4 |
Specificity | This antibody detects NCF-4 (Internal). It is expected to recognise both reported isoforms (NP_000622.2 and NP_038202.1). |
Formulation | Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Immunoaffinity chromatography |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens neutrophil cytosolic factor 4 (NCF4), transcript variant 1 |
Database Link | |
Background | The protein encoded by this gene is a cytosolic element of nicotinamide adenine dinucleotide phosphate-oxidase. Upon neutrophil stimulation, this protein and other cytosolic elements are sent to the cell membrane from the cytosol to form a complex which produces phagocytic oxygen radicals. Two motifs found in this protein, an SH3 domain and a PC motif, are significant to protein-protein interactions. Through interaction with the SH3 domain, this gene is responsible for the downregulation of NADPH-oxidase. Alternative splicing has been observed in this gene; however, the effects they have on gene function is unknown. |
Synonyms | Neutrophil cytosol factor 4, SH3PXD4, p40-phox |
Reference Data | |
Protein Pathways | Leukocyte transendothelial migration |
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