GABA A Receptor beta 3 (GABRB3) (400-411) Goat Polyclonal Antibody

CAT#: AP22582PU-N

GABA A Receptor beta 3 (GABRB3) (400-411) goat polyclonal antibody, Aff - Purified

Product Images

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GABRB3 antibody followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/8000.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
• Reactivities: Canine, Equine, Hamster, Human, Monkey, Mouse, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human GABRB3 (NP_000805.1; NP_068712.1)
• Specificity: This antibody detects GABRB3 (Internal).
  It is expected to recognize both reported isoforms (NP_000805.1, NP_068712.1).
• Formulation: Tris saline, pH~7.3
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Stabilizer: 0.5% BSA
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens gamma-aminobutyric acid type A receptor beta3 subunit (GABRB3), transcript variant 1
• Database Link:
  Entrez Gene 14402 MouseEntrez Gene 24922 RatEntrez Gene 2562 Human
• Background: GABRB3 is a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family.
• Synonyms: GABRB-3, GABA A receptor subunit beta-3

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction