Plin3 Goat Polyclonal Antibody

CAT#: AP22588PU-N

Plin3 goat polyclonal antibody, Purified

Product Images

WB Image for Antibody (0.1 ug/ml) staining of Rat Skin lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  IHC Image for Mouse Spleen (formalin-fixed, paraffin-embedded) stained with M6PRBP1 antibody followed by biotinylated anti-goat IgG secondary antibody LS-D3, alkaline phosphatase-streptavidin and chromogen.

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  IHC Image for Mouse Testis (formalin-fixed, paraffin-embedded) stained with M6PRBP1 antibody followed by biotinylated anti-goat IgG secondary antibody LS-D3, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/16000.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1 - 3 µg/ml.
• Reactivities: Mouse, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of mouse M6PRBP1
• Specificity: This antibody reacts to Mannose-6-phosphate Receptor Binding Protein 1 (M6PRBP1).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Mus musculus perilipin 3 (Plin3)
• Database Link:
  Entrez Gene 316130 RatEntrez Gene 66905 Mouse
• Background: Mannose 6-phosphate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. M6PRBP1 interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo.
• Synonyms: M6PRBP1; PP17; TIP47