ARMET (MANF) (C-term) Rabbit Polyclonal Antibody

CAT#: AP22598PU-N

ARMET (MANF) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of MANF in mouse brain tissue lysate with MANF antibody at (A) 1 and (B) 2 ug/ml. Below: Immunohistochemistry of MANF in human brain tissue with MANF antibody (AP22598PU-N) at 2.5 ug/ml.

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  Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with ARMET antibody AP22598PU-N at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1 - 2 µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: ARMET antibody was raised against 12 amino acid peptide from near the carboxy terminus of human MANF
• Specificity: This antibody reacts to Arginine-rich, Mutated In Early Stage Tumors (ARMET).
• Formulation: PBS containing 0.02% sodium azide.
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 1 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens mesencephalic astrocyte derived neurotrophic factor (MANF)
• Database Link:
  Entrez Gene 74840 MouseEntrez Gene 315989 RatEntrez Gene 7873 Human
• Background: The ARP gene encodes a highly conserved arginine-rich protein of unknown function. The presence of a specific mutation changing codon 50 from ATG to AGG or deletion of codon 50 of the ARP gene in different tumor types has been reported. In particular, mutation is associated with pancreatic cancer.
• Synonyms: Arginine-rich protein, MANF

Reference Data

• Protein Families: Druggable Genome, Secreted Protein