ROCK2 Rabbit Polyclonal Antibody

CAT#: AP22644PU-N

ROCK2 rabbit polyclonal antibody, Purified

Product Images

Western Blot analysis of various cell lysates

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  Human Adrenal (formalin-fixed, paraffin-embedded) stained with ROCK2 antibody AP22644PU-N at 1/100 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Prostate (formalin-fixed, paraffin-embedded) stained with ROCK2 antibody AP22644PU-N at 1/100 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 1/100.
  Western Blot: 1/2000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: ROCK2 antibody was raised against synthetic peptide
• Specificity: This antibody reacts to Rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2).
• Formulation: HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Gene Name: Homo sapiens Rho associated coiled-coil containing protein kinase 2 (ROCK2), transcript variant 1
• Database Link:
  Entrez Gene 19878 MouseEntrez Gene 25537 RatEntrez Gene 9475 Human
• Background: ROCK2 is a ROCK protein serine/threonine kinase that is one of the targets for the small GTPase Rho. ROCK2 regulates the formation of actin stress fibers and focal adhesions, cytokinesis, smooth muscle contraction, and the activation of c-fos serum response element.
• Synonyms: ROCK-2, p164ROCK-2, KIAA0619

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Axon guidance, Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, TGF-beta signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway