BMP4 Rabbit Polyclonal Antibody

CAT#: AP22650PU-N

BMP4 rabbit polyclonal antibody, Aff - Purified

Product Images

Formalin-Fixed, Paraffin-Embedded Human Kidney stained with BMP4 antibody at 5 ug/ml after heat-induced antigen retrieval.

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  Formalin-Fixed, Paraffin-Embedded Human Lung stained with BMP4 antibody at 5 ug/ml after heat-induced antigen retrieval.

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  Formalin-Fixed, Paraffin-Embedded Human Placenta stained with BMP4 antibody at 5 ug/ml after heat-induced antigen retrieval.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 0.5 - 4 µg/ml.
• Reactivities: Chicken, Human, Mouse, Rabbit, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 395 of Human BMP-4
• Specificity: This antibody recognizes Bone Morphogenetic Protein 4 (BMP4).
• Formulation: PBS, pH 7.2 containing 30% Glycerol, 0.5% BSA, 0.01% Thimerosal
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography
• Storage: Upon receipt, store the antibody at -20°C or (in aliquots) at -70°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 1
• Database Link:
  Entrez Gene 12159 MouseEntrez Gene 25296 RatEntrez Gene 652 Human
• Background: Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Through molecular cloning, 7 BMP cDNAs, designated BMP1 through BMP7, have been recovered. BMP2 through BMP7, are members of the transforming growth factor-beta superfamily of regulatory molecules. Transcript variants utilizing alternative promoters and alternative non-coding first exons have been described in the literature.
• Synonyms: BMP2B, BMP-2B, BMP-4, DVR4, Bone morphogenetic protein 4

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, TGF-beta signaling pathway