alpha 2 Macroglobulin (A2M) (C-term) Rabbit Polyclonal Antibody

CAT#: AP22655PU-N

alpha 2 Macroglobulin (A2M) (C-term) rabbit polyclonal antibody, Purified

Product Images

Human Liver (formalin-fixed, paraffin-embedded) stained with A2M antibody at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1 µg/ml.
• Reactivities: Human, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to C-terminal residues of Human A2M (Alpha-2-macroglobulin precursor)
• Specificity: This antibody recognizes Alpha-2-macroglobulin (A2M).
• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Stabilizer: 50% Glycerol
  Preservative: 0.01% Sodium Azide
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens alpha-2-macroglobulin (A2M)
• Database Link:
  Entrez Gene 24153 RatEntrez Gene 2 Human
• Background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
• Synonyms: Alpha-2-M, CPAMD5, Alpha 2 macroglobulin

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades