SRC (92-109) Rabbit Polyclonal Antibody

CAT#: AP22683SU-N

SRC (92-109) rabbit polyclonal antibody, Serum

Product Images

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with SRC antibody AP22683SU-N at 1/250 followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 1/250.
  Western Blot: 1/1000.
• Reactivities: Bovine, Bat, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Xenopus
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: SRC antibody was raised against an 18 residue synthetic peptide based on the sequence from the SH3 domain of human Src (residues 92-109) was synthesized and the peptide coupled to KLH.
• Specificity: This antibody reacts to Proto-Oncogene Protein Tyrosine Kinase SRC (SRC) at 92-109.
• Formulation: State: Serum
  State: Liquid serum
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens SRC proto-oncogene, non-receptor tyrosine kinase (SRC), transcript variant 1
• Database Link:
  Entrez Gene 20779 MouseEntrez Gene 83805 RatEntrez Gene 6714 Human
• Background: SRC is a non-receptor tyrosine kinase belonging to the Src subfamily. Src was the first proto-oncogene to be described and one of the first molecules demonstrated to have tyrosine kinase activity. Src is involved in a wide variety of cellular processes, including proliferation, differentiation, motility, and adhesion. Alternative splicing has been observed, including a neuron specific form with a 6 amino acid insert in the amino-terminal half of the c-src protein.
• Synonyms: c-Src, pp60c-src

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Stem cell relevant signaling - JAK/STAT signaling pathway
• Protein Pathways: Adherens junction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Focal adhesion, Gap junction, GnRH signaling pathway, Tight junction, VEGF signaling pathway