SRC (N-term) Rabbit Polyclonal Antibody

CAT#: AP22686PU-N

SRC (N-term) rabbit polyclonal antibody, Purified

Product Images

Human Placenta (formalin-fixed, paraffin-embedded) stained with SRC antibody AP22686PU-N at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Uterus (formalin-fixed, paraffin-embedded) stained with SRC antibody AP22686PU-N at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunofluorescence: 1/10 - 1/50.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: SRC antibody was raised against kLH conjugated synthetic peptide selected from the N-terminal region of human SRC.
• Specificity: This antibody reacts to Proto-Oncogene Protein Tyrosine Kinase SRC (SRC).
• Formulation: PBS containing 0.09% sodium azide
  State: Purified
  State: Liquid purified Ig fraction
• Purification: Protein G Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens SRC proto-oncogene, non-receptor tyrosine kinase (SRC), transcript variant 1
• Database Link:
  Entrez Gene 20779 MouseEntrez Gene 6714 Human
• Background: SRC is a non-receptor tyrosine kinase belonging to the Src subfamily. Src was the first proto-oncogene to be described and one of the first molecules demonstrated to have tyrosine kinase activity. Src is involved in a wide variety of cellular processes, including proliferation, differentiation, motility, and adhesion. Alternative splicing has been observed, including a neuron specific form with a 6 amino acid insert in the amino-terminal half of the c-src protein.
• Synonyms: c-Src, pp60c-src

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Stem cell relevant signaling - JAK/STAT signaling pathway
• Protein Pathways: Adherens junction, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Focal adhesion, Gap junction, GnRH signaling pathway, Tight junction, VEGF signaling pathway