Fas Ligand (FASLG) (N-term) Rabbit Polyclonal Antibody

CAT#: AP22688PU-N

Fas Ligand (FASLG) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Human Prostate (formalin-fixed, paraffin-embedded) stained with FASLG antibody AP22688PU-N at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: FASLG antibody was raised against peptide mapping near the amino terminus of rat FAS-L
• Specificity: This antibody reacts to TNF Ligand Superfamily, Member 6 (FASLG).
• Formulation: PBS containing 0.09% sodium azide, 0.2% gelatin
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens Fas ligand (FASLG), transcript variant 1
• Database Link:
  Entrez Gene 25385 RatEntrez Gene 356 Human
• Background: Apoptosis antigen ligand 1 is the ligand for FAS. Both are transmembrane proteins. Interaction of FAS with its ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Defects in TNFSF6 may be related to some cases of systemic lupus erythematosus (SLE).
• Synonyms: FASLG, APT1LG1, FASL, TNFSF6, CD95L protein, APTL

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Allograft rejection, Apoptosis, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Pathways in cancer, Type I diabetes mellitus