NOTCH2 (2457-2471) Rabbit Polyclonal Antibody

CAT#: AP22760PU-N

NOTCH2 (2457-2471) rabbit polyclonal antibody, Purified

Product Images

Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with NOTCH2 antibody followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

• 

  Human Liver (formalin-fixed, paraffin-embedded) stained with NOTCH2 antibody followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

• 

  Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with NOTCH2 antibody followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/1000.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivities: Human, Monkey
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from human NOTCH2 (aa 2457-2471)
• Specificity: This antibody reacts to Notch Homolog 2 (NOTCH2) at aa 2457-2471.
• Formulation: PBS containing 0.09% sodium azide
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein G Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens notch 2 (NOTCH2), transcript variant 1
• Database Link:
  Entrez Gene 4853 Human
• Background: NOTCH2 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions.
• Synonyms: Notch 2, hN2

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Dorso-ventral axis formation, Notch signaling pathway