Caspase 3 (CASP3) (full length) Rabbit Polyclonal Antibody

CAT#: AP22764PU-N

Caspase 3 (CASP3) (full length) rabbit polyclonal antibody, Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Western Blot: 1/1000.
Reactivities Bovine, Canine, Chicken, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Yeast
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant human Caspase-3 protein (full length)
Specificity This antibody reacts to Caspase 3 (CASP3).
Formulation PBS containing 0.09% azide and 50% glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A Chromatography
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant alpha
Background Caspase 3 is synthesized as an inactive proenzyme that undergoes proteolytic cleavage to produce 2 subunits, termed p20 and p11. These subunits dimerize to form the active enzyme. Caspase 3 proteolytically cleaves and activates other proteins. Caspase 3 has been associated with apoptosis.
Synonyms CASP-3, CASP3, CPP32, CPP-32, Yama protein, Apopain, SCA-1, SCA1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protease
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, Huntington's disease, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Parkinson's disease, Pathways in cancer, Viral myocarditis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.