Caspase 3 (CASP3) (full length) Rabbit Polyclonal Antibody

CAT#: AP22764PU-N

Caspase 3 (CASP3) (full length) rabbit polyclonal antibody, Purified

Product Images

Human Spleen (formalin-fixed, paraffin-embedded) stained with CASP3 antibody at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/1000.
• Reactivities: Bovine, Canine, Chicken, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Yeast
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant human Caspase-3 protein (full length)
• Specificity: This antibody reacts to Caspase 3 (CASP3).
• Formulation: PBS containing 0.09% azide and 50% glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant alpha
• Database Link:
  Entrez Gene 12367 MouseEntrez Gene 25402 RatEntrez Gene 694473 MonkeyEntrez Gene 836 Human
• Background: Caspase 3 is synthesized as an inactive proenzyme that undergoes proteolytic cleavage to produce 2 subunits, termed p20 and p11. These subunits dimerize to form the active enzyme. Caspase 3 proteolytically cleaves and activates other proteins. Caspase 3 has been associated with apoptosis.
• Synonyms: CASP-3, CASP3, CPP32, CPP-32, Yama protein, Apopain, SCA-1, SCA1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Epithelial cell signaling in Helicobacter pylori infection, Huntington's disease, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Parkinson's disease, Pathways in cancer, Viral myocarditis