MMP3 Rabbit Polyclonal Antibody

CAT#: AP22793PU-N

MMP3 rabbit polyclonal antibody, Purified

Product Images

Western Blot analysis of MMP3 expression with Jurkat cell lysate. Both full length (55kD) and cleaved form (21kD) detected.

• 

  Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 0.5 - 4 µg/ml.
• Reactivities: Equine, Human, Mouse, Rabbit, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 465 of Rat MMP-3
• Specificity: The antibody recognizes the MMP-3.
  The antibody detects the 55 kD full length and the 21 kD cleavage fragment of MMP-3.
• Formulation: PBS containing 30% Glycerol, 0.5% BSA and 0.01% Thimerosal
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens matrix metallopeptidase 3 (MMP3)
• Database Link:
  Entrez Gene 17392 MouseEntrez Gene 171045 RatEntrez Gene 4314 Human
• Background: MMP3 is a Metallopeptidase M10A type protease. Human fibroblast stromelysin/MMP3 is a proteoglycanase with a wide range of substrate specificities. It is a secreted metalloprotease produced predominantly by connective tissue cells. MMP3 is capable of degrading proteoglycan, fibronectin, laminin, and type IV collagen. Expression has been documented in breast carcinoma, wound healing and chronic inflammatory diseases.
• Synonyms: Stromelysin-1, SL-1, Matrix metalloproteinase-3, Transin-1, MMP3, STMY1

Reference Data

• Protein Families: Druggable Genome, Protease