CD19 (393-421) Rabbit Polyclonal Antibody

CAT#: AP22796PU-N

CD19 (393-421) rabbit polyclonal antibody, Aff - Purified

Product Images

Human Spleen (formalin-fixed, paraffin-embedded) stained with CD19 antibody followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Tonsil (formalin-fixed, paraffin-embedded) stained with CD19 antibody followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: CD19 antibody was raised against kLH-conjugated synthetic peptide between amino acids 393-421 from C-terminal region of human CD19.
• Specificity: This antibody reacts to CD19 Antigen (CD19) at aa 393-421.
• Formulation: PBS containing 0.09% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Purification: Immunoaffinity purified
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens CD19 molecule (CD19), transcript variant 2
• Database Link:
  Entrez Gene 930 Human
• Background: Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
• Synonyms: Leu-12, B-cell marker

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: B cell receptor signaling pathway, Hematopoietic cell lineage, Primary immunodeficiency