Non Neuronal Enolase (ENO1) (178-205) Rabbit Polyclonal Antibody

CAT#: AP22805PU-N

Non Neuronal Enolase (ENO1) (178-205) rabbit polyclonal antibody, Ig Fraction

Product Images

Human Adrenal (formalin-fixed, paraffin-embedded) stained with ENO1 antibody followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Breast (formalin-fixed, paraffin-embedded) stained with ENO1 antibody followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: FC, IF, IHC, WB
• Recommended Dilution: Flow Cytometry: 1/10 - 1/50.
  Immunofluorescence: 1/10 - 1/50.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: This ENO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the Central region of human ENO1.
• Specificity: This antibody reacts to Alpha Enolase (ENO1).
• Formulation: PBS containing 0.09% sodium azide as preservative
  State: Ig Fraction
  State: Liquid purified Ig fraction
• Purification: Ammonium Sulfate Precipitation
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens enolase 1, (alpha) (ENO1), transcript variant 1
• Database Link:
  Entrez Gene 2023 Human
• Background: This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
• Synonyms: Enolase 1, ENO1L1 Non-neural enolase, NNE, Plasminogen-binding protein, MBP-1, MPB-1, MBPB1, MPB1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Glycolysis / Gluconeogenesis, Metabolic pathways, RNA degradation