APRIL (TNFSF13) (Extracell. Dom.) Rabbit Polyclonal Antibody

CAT#: AP22855PU-N

APRIL (TNFSF13) (Extracell. Dom.) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of APRIL expression in Jurkat cells with APRIL antibody (AP22855PU-N) at 1 ug/ml (A), 2 ug/ml (B), and 4 ug/ml (C).

• 

  Immunohistochemistry of APRIL in human prostate tissue with APRIL antibody (AP22855PU-N)at 10 ug/ml.

• 

  Human Lung (formalin-fixed, paraffin-embedded) stained with TNFSF13 antibody AP22855PU-N at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

• 

  Human Spleen (formalin-fixed, paraffin-embedded) stained with TNFSF13 antibody AP22855PU-N at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Native rat liver Grp58 protein
• Specificity: This antibody reacts to TNF Ligand Superfamily, Member 13 (TNFSF13/APRIL).
• Formulation: PBS containing 0.02% sodium azide.
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens tumor necrosis factor superfamily member 13 (TNFSF13), transcript variant alpha
• Database Link:
  Entrez Gene 69583 MouseEntrez Gene 8741 Human
• Background: Northern blot analysis revealed weak expression restricted to a few tissues: transcripts of 2.1 and 2.4 kb in prostate and a transcript of 1.8 kb in peripheral blood leukocytes. All tumor cell lines, however, strongly expressed the TNFSF13 2.1-kb transcript, and expression of extracellular or full-length TNFSF13 led to increased proliferation of various cell lines.
• Synonyms: TNFSF13, TALL2, TALL-2, ZTNF2, TRDL-1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction